Aiming at the problem of excessive vibration and noise of an internal combustion engine produced by a company at a speed of 780 r/min, a vibration and noise test was performed and the reason for the excessive vibration and noise was obtained, and the distribution law of the noise and vibration of the internal combustion engine was obtained to provide certain experimental basis for subsequent suspension design of the internal combustion engine. The vibration signals of the internal combustion engine were tested at speeds of 780, 820, 2 200 r/min under different load conditions, as well as the transient noise signal of the internal combustion engine under acceleration conditions of 750~3 390 r/min. Frequency spectrum analysis on the measured steady-state signal was performed, the vibration intensity was calculated, the influence of the engine speed and load on noise was obtained, and order analysis on the transient signal was performed to obtain the change of each order signal with the speed and the main contribution order times. Finally the mode of the suspension system of the internal combustion engine was designed based on the above research results. The analysis results show that under steady-state conditions, the fundamental frequency increases as the speed increases, and the vibration intensity of the Z axis is greater than that of the X and Y axes at the same speed;the vibration intensity of the internal combustion engine at 780 r/min is greater than that at 820 r/min. It shows that the internal combustion engine has resonance at 780 r/min. The noise is mainly composed of 1, 2, 4, 6, and 8 order mechanical noises. Mechanical noise is the mechanical noise order and its harmonic order caused by the bearing or static eccentricity. It provides basis for the subsequent optimization of the internal combustion engine.