In order to study the influence of machining parameters on the surface integrity of TC4 titanium alloy by ultrasonic-assisted rolling strengthening,a 4×4 orthogonal test based on spindle speed,feed rate,static pressure and machining times was designed.The surface microstructure,residual stress,hardness and roughness of the samples were observed and analyzed.The results show that the surface residual stress and hardness first increase and then decrease with the increase of the spindle speed and feed speed,gradually increase with the increase of the static pressure,and gradually decrease with the increase of the machining times;the surface roughness increases gradually with the increase of spindle speed and feed rate,and decreases with the increase of static pressure and machining times.After processing,the surface integrity of the sample is effectively improved,the scratch defects are eliminated,and the surface smoothness is improved;and a favorable residual compressive stress is formed with a maximum value of -431.063 MPa,the surface microhardness is increased by 38.1%,the surface roughness is decreased by 92.7%.