Aimed at contradiction between the unbalanced load and synchronization precision of the hydraulic synchronization drive system under the working condition of bias load, the idea of coordinated control of synchronous motion control and load balance regulation is put forward. The idea is that a load balance regulation loop is specially designed to eliminate bias load effect besides the traditional synchronous motion control loop. Four kinds of hydraulic synchronous lifting systems capable of eliminating bias load effect with double-cylinder were designed especially besides the traditional synchronous motion control circuit based on accumulator controlled by high-speed on-off valve, accumulator controlled by proportional valve, proportional relief valve and proportional pressure reducing valve respectively, and then their form of structure and working principle were also compared with analysis. The study provides a new way for higher precision of hydraulic synchronous movement in the bias load conditions.