Based on the theory of multibody system kinematics, the topology structure relationship of the multibody machine tools and axis error term elements of each motion axis were analyzed. The geometric error model of multiaxis machine tool movement space was established. Error compensation platform was developed based on the Labview, and the error compensation experiment was carried out. By compared each axis positioning error and numerical control (NC) machining code before and after the compensation, the established error model is verified correct, and the compensation method is feasible.