For designing the virtual prototype of hydropneumatic suspension system, a method of cosimulation based on ADAMS and AMESim was put forward. The 1/12 vehicle dynamic model of hydropneumatic suspension system was established in ADAMS. The hydraulic and control system model was accomplished in AMESim. Last the interface port between the two simulation software was set. Through cosimulation, the dynamic responses analyses under different shock inputs were fulfilled. Virtual test results shows a good consistency of working characteristics of the practical hydropneumatic suspension system and verifies the validity of the established model.