Curved Guideway—the core component of billet mold—as the research object. Finite element model of curved guideway was established by HyperMesh. Finite element analysis of static and dynamic characteristics were obtained by using ANSYS Workbench. In addition, maximum deformation, maximum stress value, natural frequency and vibration mode were obtained during static and dynamic analysis. Finally, the crosssectional dimensions of guideway were optimization designed by using Design Explorer module of ANSYS Workbench. The result shows that in a satisfaction of strength requirement premise, the maximum deflection deformation of guideway is reduced, the total weight of guideway is reduced, the low order natural frequency of guideway is raised,the design cycle of guideway is decreased and market competitiveness is raised. The research provides effective optimization method for the structure of the product.