The characteristics of the rotary indexing processing technology were analyzed theoretically. According to the actual production, 3D design software was used to design rotary indexing machine virtual prototype.The interaction between JavaScript language and VRML language was used to realize the rotary indexing machining simulation. According to the experimental results, the rotary indexing machine was designed and manufactured, and the actual processing operation was done. Through verification, the rotary indexing machine processing is high efficiency and stable, high machining accuracy can be achieved.