ccording to the actual project needs and combined with the first law of thermodynamics, a company’ s ES series high speed motorized spindle system is taken as an example. Its heat source and heat dissipation characteristics were analyzed, and the main heat source heat production parameters and the coefficient of heat transfer and thermal analysis were calculated. Comprehensive analysis results, through finite element analysis (FEA) software ANSYS to establish finite element model (FEM) and to do the thermodynamic simulation research, it can be concluded that motorized spindle system of each part of the steady state temperature distribution in the cloud and when reaching thermal equilibrium, the curve of heat source temperature changes over time. Combining with experimental analysis verification shows, the simulation results and motorized spindle to improve reference opinions are put forward.