In view of the problem of wiring difficulties, the deployment of high cost, poor maintainability and limited monitoring scope existing in bearing fault diagnosis system for wiring signal acquisition at present, the wireless data acquisition module for bearing vibration signal is designed. The module adopting STM32F103RET6 as the main control chip was used of the piezoelectric acceleration sensor to collect the vibration signal of the bearing, the ADS8344 and DAC8531 were used for Analog to Digital/Digital to Analog(AD/DA), and then through Bluetooth technology,wireless transmission was realized. Finally, using the data acquisition(DAQ) card and the virtual instrument based on LabVIEW as the development platform, the operation condition of the bearing is monitored online, which provides a new idea for the bearing fault diagnosis.