The new balance calibration platform was designed under the guidance of the optimization driven design method. In the scheme design stage,the two movable gantry with the fixed loading end was chosen to achieve multi axial loading,the servo electric cylinder was chosen to achieve high precision force control.For gantry,gear rack with linear guide was used to achieve high precision movement.After the scheme was determined, the topology optimization was applied to the parts of the gantry, and then the dimensions of the two parts of the gantry and fixed ends were optimized.After optimization, the deformation of the main loading condition was reduced by 30.6%, and the weight of the gantry was reduced by 6.9%.Finally the platform can achieve multi axis, high precision force control and coordinate loading. Compared with the existing calibration platform, manual operation is reduced and the reliability of the calibration results is improved.