In order to study the relationship between the ultrasonic vibration parameters（amplitude, frequency）and the cutting temperature of the cortical bone, a threedimensional simulation model of ultrasonic vibration drilling was established by finite element software. An experiment comparison of cortical bone temperature for ultrasonic vibration drilling and conventional drilling using fresh porcine femur was made to validate the model. The result shows that vibrational drilling can significantly reduce the cutting temperature in drilling of cortical bone；the model is credible to some extent; the cutting temperature tends to decrease with the increase of vibrational frequency and amplitude within research range.