In order to solve the problem that metal oxide semiconductor gas sensor is easily affected by external environment temperature and produce output drift, the paper puts forward a compensation method based on the temperature of negative feedback. By constructing proper thermistor, the paper designed an adjustable switching circuit to provide the heating voltage sensor and a stable working condition of sensitive materials was guaranteed. By comparing experiments with TGS2610 gas sensor, the error can be reduced from -40%, +70% to ±10.