Information technology has a strong penetration, providing effective solutions to the challenges faced by the manufacturing industry. The information technology used to improve the core competitiveness of the manufacturing industry has become a significant global trend. The basic concepts of Industry 4.0 and cloud manufacturing were introduced. Industry 4.0 refers to the fourth industrial revolution, which is characterized by the extensive application of cyberphysical systems (CPS) in the manufacturing environment.Cloud manufacturing is a new service manufacturing model based on the concept and method of cloud.In order to better understand the two concepts and the relationship between them, and a detailed comparative analysis was carried out from the goal, the core technology, the operation mode and the architecture.