According to the wear theory, the accuracy retention model of sliding guide of machine tool was derived. The No. 100 guideway lubricating oil was used as the lubricating medium, under the boundary lubrication condition, the selfdeveloped guideway bench testing machine was used to carry out the equidistant nonisovelocity sliding experiment to verify the accuracy retention model. The established accuracy retention model can be used to predict the linearity attenuation of machine tool sliding guideway very well. The accuracy retention time and the working condition parameters of sliding guideway were quantitatively analyzed by using the established model