When the laser sensor at the end of the industrial robot was used to detect the position and pose of the workpiece, in order to solve the coordinate calibration problem of the workpiece in the detection process, a workpiece coordinate calibration system based on laser tool was designed. The main principle of the system was to obtain two data points on each side of the two intersecting lines of the workpiece by using the laser tool, and to obtain the workpiece coordinate system with the intersection point as the origin after the calibration operation.The data point acquisition program and coordinate operation program were designed based on ABB industrial robot system.Taking IRB1410 robot as the actuator,IL-300 sensor as the laser tool and R-20 Radian laser tracker as the calibration equipment,a debugging and calibration platform was built. The results show that the coordinate calibration system based on laser tool is simple in structure and the calibration error is within a certain range. 