The Sinumerik 840Dsl CNC system was selected as the development platform and the roller grinding was taken as the research object, the roll grinding system was developed. In the Qt Creator crossplatform development framework, the GUI application was developed. The OPC UA communication technology was used to obtain the CNC machine information in real time. The machine processing information was saved and managed by using the MySQL database. The user global variables were designed, the roll processing G code program was generated, and the roll grinding was realized. Compared with traditional software development method, this method has the advantages of good openness and strong compatibility, which is conducive to the interconnection between manufacturing units.So the problem of “information island” is effectively solved, and the processing efficiency is improved.