The dynamic performance of the turnout area is one of the main factors determining the speed and safety of the vehicle, and the wheel polygonal wear will significantly influence the wheelrail interaction force and the vibration characteristics of the key parts of the bogie. Taking No. 18 movable core rail turnout as the research object, the vehicleturnout coupling dynamics model was established. The measured vibration data of the train lateral crossing the turnout area were analyzed, and the influence of different polygonal amplitude wheels on the vibration transmission of various parts of the vehicle body was analyzed. The results show that when the train passes the turnout section, increasing the polygonal amplitude has a great influence on the damping effect of the key parts; when the amplitude of the polygon is 014 mm, the dynamic response amplitude is larger, and the lateral force is close to the limit of lateral passing turnout; the maximum value position of the derailment coefficient changes with the increase of the amplitude of the polygon; the first suspension can not effectively reduce the vibration caused by polygonal wheels, and the second suspension can eliminate part of the vibration energy, but the lateral damping effect is still not ideal in the core rail section.