Taken the flexible intelligent manufacturing production line as the research object, a virtual system scheme designed by using the ABB robot virtual software was introduced. The system is an intelligent manufacturing production line simulation system composed of 3 robots, 4 CNC machine tools and a variety of equipments. The three robots can coordinate the operation with the equipment, and can process, polish, clean, detect and pack the goods in turn according to the processing technology of the product, so as to realize unmanned production. Mechanical devices and Smart components of each device were created to realize I/O signal connection between the system and components. The running program of the robot was written, and its running route was planned, so as to realize the running of the simulation system. The virtual system synchronizes with the actual production. Taking the real automobile end cover parts as the processing example, it provides theoretical basis and test platform for designer, the field debugging time is shortened, the production line design, debugging and improvement cost is reduced, and it can be used to guide field production