The working characteristics of the force and torque load of a CNC table and the working principle of YRT table bearing and clamping system under working load were analyzed.The calculation formula of the deformation of the table spindle under 6-DOF load was derived, and the influence of the load on the deformation and accuracy of the table was summarized.The methods to test the deformation of table under axial load, radial load, torque load and twist load were designed.It provides reference for the design and calculation of bearing support structure and clamping structure of CNC table, and provides experiment and inspection method for CNC table load experiment.