In order to cope with the inspection difficulties of diameters and locations of the film cooling holes on hollow turbine blade, a noncontact fiveaxis vision measuring system was designed based on machine vision measuring and multiaxis motion controlling technologies. The system was composed of coordinate measuring machine, twoaxis turntable, industrial visual probe and special fixture of blade, which possessed three moving degrees of freedom and two rotational degrees of freedom. In the measuring procedure, the rotation of the target blade was realized by using the twoaxis turntable, and the moving of the industrial visual probe was realized by using the coordinate measuring machine,by which the visual probe could be focused on the exit surface of the measured hole and then the sharp images were captured. The geometrical dimensions and distribution positions of the hole were obtained through image processing and other steps. To verify the practicability and effectiveness of the system, diameters and center coordinates of a row of film cooling holes on a hollow turbine blade were measured. The experimental results show that the designed measuring system can be utilized to measure the diameters and center coordinates of film cooling holes, and the repeatability accuracy can meet the application requirements.