The traditional packaging method of respiratory assistant guide wire is artificial packaging.In order to improve the packaging efficiency,a kind of automatic packaging machine for respiratory assistant guide wire was designed.The product packaging process was summarized and studied,combined with ergonomics,the corresponding mechanisms were designed to imitate the production action of workers to achieve the packaging function.In the design of the packaging machine,the motor and air pressure were used as the power source to drive the mechanism to work synchronously,and relevant PLC control technology was used to coordinate the work of each mechanism,so the automatic packaging function could be realized.The results show that the packaging machine with multi position fixture can not only guarantee the packaging quality,but also realize the one-time packaging of multiple guide wires,reduce the labor intensity of workers and improve the packaging efficiency of respiratory guide wires.The results provide reference for automatic packaging of respiratory guide wire.