In order to study the size and distribution of aerodynamic noise in a twin-screw air compressor, a three-dimensional model of the twin-screw rotor and a flow field model of the air compressor were established. Combining fluid dynamics calculation method with acoustic finite element technology, the influence of rotor center distance and tooth tip clearance on broadband noise of twin-screw air compressor was studied. The results show that the sound power level at the edge of the air inlet of the compressor is the lowest; the sound power level of the part in contact with the air inlet and gradually approaching the volume of the rotor is lower, while the sound power level of the rotor meshing part and the air outlet is the largest; the magnitude of broadband noise increases as the pressure difference increases; when the tooth tip clearance is 0.2 mm, the broadband noise of the air compressor is smaller; when the rotor center distance is 81.2 mm, the broadband noise of the air compressor is smaller.