In order to shorten the bearing design,analysis and calculation cycle and improve the efficiency and accuracy of bearing design,the special flexible ball bearing for harmonic reducer was taken as the research object.The design and parameter correction module,bearing design parameter detection module,contact stress calculation module and ABAQUS finite element joint analysis and calculation module were developed by using MATLAB GUI software platform.The designed analysis system was easy to use,only needed to input the main bearing,the parameters design,maximum contact stress calculation and finite element analysis of the bearing could be completed and the results could be displayed in the system interface or output as txt and Excel files.The design method of special flexible ball bearing for harmonic reducer was introduced,the verification and analysis of the designed bearing parameters were carried out,and many engineering applications had been carried out.The results show that the system is efficient and reliable.