Based on the need of disinfection and epidemic prevention under new crown epidemic,a disinfection and epidemic prevention robot with a shock-absorbing and buffering mobile chassis was designed.The disinfection module integrated with ultraviolet and spray disinfection functions could automatically rise and fall to meet the disinfection needs of areas with different heights.The mobile chassis could complete map construction and autonomous navigation,and the disinfection module could meet the needs of thorough disinfection,no dead corners and high-level disinfection.The speed motion model of the mobile disinfection and epidemic prevention robot was analyzed and established; a simulation environment was built,a simulation environment map was obtained,and autonomous navigation in this environment was implemented.The results show that the designed navigation system is safe and reliable,and can realize the greening and automation of indoor space disinfection.