By the spatial coordinate transformation theory and conjugate theory, the mathematic model of cylindrical indexing cam mechanism is established. Using Pro/E software for three dimensional parametric modelling capabilities for a specific and precise modelling of cylindrical indexing cam design, its 3D solid model is built. And its dynamics and kinematics simulation was analyzed by ADAMS software. Simulation results show that the Correctness of the agency model，Be of great practical value conclusion，It has the guidance to the cylindrical indexing cam mechanism design, processing, installation.