Under the epidemic situation,in order to solve the requirements of narrow space,complex curved surface,non-contact and safe automatic disinfecting operation,a mobile automatic disinfecting mechanical control system based on double-vehicle splicing based on multi-sensor measurement was designed.A dual-vehicle splicing omnidirectional auto guided vehicle (AGV) that could be quickly disassembled and assembled was designed to solve the problem of transportation in narrow spaces.At the same time,a laser navigation sensor was used to build a scene coordinate system to precisely locate the equipment position,so that the positioning accuracy during equipment operation could reach ±5 mm.A scanning and disinfecting machinery with laser ranging sensor,obstacle avoidance sensor,and disinfecting device was designed,and a correction algorithm was designed based on the KUKA robot sensor interface (RSI) to realize online pose adjustment and safety protection of the machinery during the disinfecting process.Finally,for the need of unmanned operation on site during the disinfecting process,a remote control network consisting of remote terminal-AGV-robot system was build.Once the disinfection instructions were issued on the remote terminal,the optimal path according to the scene parameters was calculated to autonomously complete the task.Furthermore,a vertical wall and arc top scene were built.During the disinfection process,the position deviation is ±3 mm,and the angle deviation is ±1.5°.The control results has a high fitting accuracy with the actual object,which increases the effective disinfection area.