Taking the structure of printed electronics inkjet printer as the research object, the dynamic characteristic was analyzed based on ANSYS Workbench platform. Aiming at the overweight problem of structure for printed electronics inkjet printer, combining with response surface method and multiobjective genetic algorithm, the structural parameters of jet printing machine were optimized under the premise of ensuring good dynamic characteristic of structure. The optimization results show that using response surface method and multiobjective genetic algorithm can obtain the optimal solution set of the printer structural optimal design problem quickly and accurately, which provides a reference for the multiobjective optimization design of product structure.