Based on UG software platform and AVL650e fouraxis vertical machining center,the realization ideas and steps of NC simulation and entity machining for Venus were introduced in detail.Aiming at the special motion relationship of AVL650e fouraxis machine tool,based on UG/Post Builder,the special postprocessing program files,machine tool files and controller files were developed for the equipment,its correctness and feasibility were verified through VERICUT simulation and processing.It provides reference for expanding the processing range of similar multi axis machine tools.