Aiming at the computing demand of low delay transmission and efficient processing of logistics status data generated by smart sensors, a framework model of AGV cloud-edge collaborative computing based on RFID-awared materials was proposed. The key technologies of AGV data acquisition and information interaction, RFID data processing, cloud-edge collaborative computing were discussed. The case study shows that the production logistics process data can be processed cooperatively at the AGV edge and cloud levels of the computing model, so as to realize active perception and independent decision-making, and to provide support for the autonomy and intelligence of the workshop.