Abstract:Advanced manufacturing technology at present and multi-axis processing CAD/CAM software PowerMILL were introduced. The process and tooling about the five axis parts “World Cup” were analyzed. The tool path setting process based on PowerMILL software for“World Cup” part was introduced, focusing on the processing strategy setting method of model area clearance in rough processing tool path setting. In the tool path setting process, the interference problem between machine spindle head and fixture was solved through the rotation of spindle, and the length of cutter was shortened, processing rigidity,efficiency and accuracy were improved.