Resin concrete generally has good mechanical properties, excellent thermal stability and great vibration resistance. The model of the ultraprecision machining center bed was established in order to study the thermal stability of the resin concrete by fully using virtual reality and collaborative simulation scheme based on Pro/E and ANSYS Workbench. The main factors that affected the thermal deformation of machine tool bed were found through analyzing the thermal deformation results of traditional cast iron material and resin concrete. Moreover the materials of machine tool and restrain conditions were optimized. The results prove that the optimized machine tool bed has good thermal stability, and theoretical basis is provided to improve the thermal stability of the ultraprecision machining centers.