Aiming at uncertain parameters and external disturbance of Numerical Control (NC) Machining Tool position servo system, this paper proposed a kind of neuron sliding mode control algorithm based on CMAC (cerebella model articulation control) by combing CMAC network with sliding mode control. The simulation results show the control method effectively reduces the chattering phenomenon in the conventional slide mode variable structure control. It also shows the position servo system has better dynamic performance, static performance and strong robustness. It can realize rapid and exact position servo control.