Abstract:ue to the small size, the relatively simple structure, and easily implanted to the body, etc., Axial Blood Pump has become research focus of artificial heart. First, an axial blood pump is designed. Then RNG κ-ε turbulence model of the numerical simulation method was used for analysis flow field distribution in blood pump, and Computational Fluid Dynamics (CFD) technology was used to simulate the internal flow field of Blood Pump. The distribution of pressure, velocity and shear stress effects were gotten through calculating analysis. Finally, the areas that hemolysis and thrombus easily to appear were summarized, and the structure of blood pump was improved according to it. The results show as compared with the original blood pump, it has a better flow output capability, and the probability for hemolysis and thrombus formation areas are lowered in the improved blood pump.