Aimed to the problem of unascertained information influencing the prediction and decision-making of the manufacturing grid service execution, the key technologies of manufacturing grid service execution are discussed. The establishment of the platform system structure, analysis of the operation model, analysis and processing of the unascertained information, multi-objective decision-making information under the condition of unascertained of Meta-model of manfacturing resource service, and flexible service scheduling under unascertained information were carried out. The corresponding solutions are given.